WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_GGGCGGR_V$SP1_Q6       ID:DB_ID:2452
C=2891; O=24; E=3.35; R=7.16; rawP=1.36e-15; adjP=2.18e-13
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000118816 NA CCNI cyclin I 10983 ENSG00000118816
2  ENSG00000166887 NA VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) 23339 ENSG00000166887
3  ENSG00000184886 NA PIGW phosphatidylinositol glycan anchor biosynthesis, class W 284098 ENSG00000184886
4  ENSG00000184481 NA FOXO4 forkhead box O4 4303 ENSG00000184481
5  ENSG00000109111 NA SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 6830 ENSG00000109111
6  ENSG00000105221 NA AKT2 v-akt murine thymoma viral oncogene homolog 2 208 ENSG00000105221
7  ENSG00000013374 NA NUB1 negative regulator of ubiquitin-like proteins 1 51667 ENSG00000013374
8  ENSG00000082641 NA NFE2L1 nuclear factor (erythroid-derived 2)-like 1 4779 ENSG00000082641
9  ENSG00000142784 NA WDTC1 WD and tetratricopeptide repeats 1 23038 ENSG00000142784
10  ENSG00000174516 NA PELI3 pellino E3 ubiquitin protein ligase family member 3 246330 ENSG00000174516
11  ENSG00000130939 NA UBE4B ubiquitination factor E4B 10277 ENSG00000130939
12  ENSG00000116604 NA MEF2D myocyte enhancer factor 2D 4209 ENSG00000116604
13  ENSG00000188021 NA UBQLN2 ubiquilin 2 29978 ENSG00000188021
14  ENSG00000139112 NA GABARAPL1 GABA(A) receptor-associated protein like 1 23710 ENSG00000139112
15  ENSG00000160445 NA ZER1 zer-1 homolog (C. elegans) 10444 ENSG00000160445
16  ENSG00000151466 NA SCLT1 sodium channel and clathrin linker 1 132320 ENSG00000151466
17  ENSG00000012822 NA CALCOCO1 calcium binding and coiled-coil domain 1 57658 ENSG00000012822
18  ENSG00000174903 NA RAB1B RAB1B, member RAS oncogene family 81876 ENSG00000174903
19  ENSG00000105357 NA MYH14 myosin, heavy chain 14, non-muscle 79784 ENSG00000105357
20  ENSG00000080802 NA CNOT4 CCR4-NOT transcription complex, subunit 4 4850 ENSG00000080802
21  ENSG00000112640 NA PPP2R5D protein phosphatase 2, regulatory subunit B', delta 5528 ENSG00000112640
22  ENSG00000167986 NA DDB1 damage-specific DNA binding protein 1, 127kDa 1642 ENSG00000167986
23  ENSG00000174282 NA ZBTB4 zinc finger and BTB domain containing 4 57659 ENSG00000174282
24  ENSG00000079459 NA FDFT1 farnesyl-diphosphate farnesyltransferase 1 2222 ENSG00000079459


Database:Transcription Target       Name:hsa_TGCGCANK_UNKNOWN       ID:DB_ID:2366
C=537; O=7; E=0.62; R=11.24; rawP=2.81e-06; adjP=0.0001
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000118816 NA CCNI cyclin I 10983 ENSG00000118816
2  ENSG00000148337 NA CIZ1 CDKN1A interacting zinc finger protein 1 25792 ENSG00000148337
3  ENSG00000184481 NA FOXO4 forkhead box O4 4303 ENSG00000184481
4  ENSG00000080802 NA CNOT4 CCR4-NOT transcription complex, subunit 4 4850 ENSG00000080802
5  ENSG00000174903 NA RAB1B RAB1B, member RAS oncogene family 81876 ENSG00000174903
6  ENSG00000174282 NA ZBTB4 zinc finger and BTB domain containing 4 57659 ENSG00000174282
7  ENSG00000142784 NA WDTC1 WD and tetratricopeptide repeats 1 23038 ENSG00000142784


Database:Transcription Target       Name:hsa_GGGTGGRR_V$PAX4_03       ID:DB_ID:2445
C=1278; O=10; E=1.48; R=6.75; rawP=1.76e-06; adjP=0.0001
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000184708 NA EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 56478 ENSG00000184708
2  ENSG00000012822 NA CALCOCO1 calcium binding and coiled-coil domain 1 57658 ENSG00000012822
3  ENSG00000119950 NA MXI1 MAX interactor 1 4601 ENSG00000119950
4  ENSG00000145901 NA TNIP1 TNFAIP3 interacting protein 1 10318 ENSG00000145901
5  ENSG00000184481 NA FOXO4 forkhead box O4 4303 ENSG00000184481
6  ENSG00000082641 NA NFE2L1 nuclear factor (erythroid-derived 2)-like 1 4779 ENSG00000082641
7  ENSG00000049759 NA NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 23327 ENSG00000049759
8  ENSG00000130939 NA UBE4B ubiquitination factor E4B 10277 ENSG00000130939
9  ENSG00000116604 NA MEF2D myocyte enhancer factor 2D 4209 ENSG00000116604
10  ENSG00000080802 NA CNOT4 CCR4-NOT transcription complex, subunit 4 4850 ENSG00000080802


Database:Transcription Target       Name:hsa_V$P53_DECAMER_Q2       ID:DB_ID:2245
C=253; O=5; E=0.29; R=17.05; rawP=1.14e-05; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000148337 NA CIZ1 CDKN1A interacting zinc finger protein 1 25792 ENSG00000148337
2  ENSG00000119950 NA MXI1 MAX interactor 1 4601 ENSG00000119950
3  ENSG00000080802 NA CNOT4 CCR4-NOT transcription complex, subunit 4 4850 ENSG00000080802
4  ENSG00000174903 NA RAB1B RAB1B, member RAS oncogene family 81876 ENSG00000174903
5  ENSG00000082641 NA NFE2L1 nuclear factor (erythroid-derived 2)-like 1 4779 ENSG00000082641


Database:Transcription Target       Name:hsa_V$MTF1_Q4       ID:DB_ID:2190
C=246; O=5; E=0.29; R=17.53; rawP=9.96e-06; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000151466 NA SCLT1 sodium channel and clathrin linker 1 132320 ENSG00000151466
2  ENSG00000148337 NA CIZ1 CDKN1A interacting zinc finger protein 1 25792 ENSG00000148337
3  ENSG00000184481 NA FOXO4 forkhead box O4 4303 ENSG00000184481
4  ENSG00000112640 NA PPP2R5D protein phosphatase 2, regulatory subunit B', delta 5528 ENSG00000112640
5  ENSG00000142784 NA WDTC1 WD and tetratricopeptide repeats 1 23038 ENSG00000142784


Database:Transcription Target       Name:hsa_V$SPZ1_01       ID:DB_ID:2103
C=225; O=5; E=0.26; R=19.17; rawP=6.47e-06; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000012822 NA CALCOCO1 calcium binding and coiled-coil domain 1 57658 ENSG00000012822
2  ENSG00000184481 NA FOXO4 forkhead box O4 4303 ENSG00000184481
3  ENSG00000080802 NA CNOT4 CCR4-NOT transcription complex, subunit 4 4850 ENSG00000080802
4  ENSG00000105221 NA AKT2 v-akt murine thymoma viral oncogene homolog 2 208 ENSG00000105221
5  ENSG00000142784 NA WDTC1 WD and tetratricopeptide repeats 1 23038 ENSG00000142784


Database:Transcription Target       Name:hsa_CAGGTG_V$E12_Q6       ID:DB_ID:2409
C=2450; O=12; E=2.84; R=4.22; rawP=1.77e-05; adjP=0.0004
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000184886 NA PIGW phosphatidylinositol glycan anchor biosynthesis, class W 284098 ENSG00000184886
2  ENSG00000184481 NA FOXO4 forkhead box O4 4303 ENSG00000184481
3  ENSG00000109111 NA SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 6830 ENSG00000109111
4  ENSG00000142784 NA WDTC1 WD and tetratricopeptide repeats 1 23038 ENSG00000142784
5  ENSG00000049759 NA NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 23327 ENSG00000049759
6  ENSG00000105357 NA MYH14 myosin, heavy chain 14, non-muscle 79784 ENSG00000105357
7  ENSG00000174516 NA PELI3 pellino E3 ubiquitin protein ligase family member 3 246330 ENSG00000174516
8  ENSG00000126947 NA ARMCX1 armadillo repeat containing, X-linked 1 51309 ENSG00000126947
9  ENSG00000080802 NA CNOT4 CCR4-NOT transcription complex, subunit 4 4850 ENSG00000080802
10  ENSG00000106078 NA COBL cordon-bleu homolog (mouse) 23242 ENSG00000106078
11  ENSG00000167986 NA DDB1 damage-specific DNA binding protein 1, 127kDa 1642 ENSG00000167986
12  ENSG00000174282 NA ZBTB4 zinc finger and BTB domain containing 4 57659 ENSG00000174282


Database:Transcription Target       Name:hsa_RCGCANGCGY_V$NRF1_Q6       ID:DB_ID:2441
C=894; O=7; E=1.04; R=6.75; rawP=7.39e-05; adjP=0.0015
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000118816 NA CCNI cyclin I 10983 ENSG00000118816
2  ENSG00000184481 NA FOXO4 forkhead box O4 4303 ENSG00000184481
3  ENSG00000080802 NA CNOT4 CCR4-NOT transcription complex, subunit 4 4850 ENSG00000080802
4  ENSG00000105221 NA AKT2 v-akt murine thymoma viral oncogene homolog 2 208 ENSG00000105221
5  ENSG00000174903 NA RAB1B RAB1B, member RAS oncogene family 81876 ENSG00000174903
6  ENSG00000174282 NA ZBTB4 zinc finger and BTB domain containing 4 57659 ENSG00000174282
7  ENSG00000142784 NA WDTC1 WD and tetratricopeptide repeats 1 23038 ENSG00000142784


Database:Transcription Target       Name:hsa_CCGNMNNTNACG_UNKNOWN       ID:DB_ID:2082
C=75; O=3; E=0.09; R=34.50; rawP=9.34e-05; adjP=0.0015
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000080802 NA CNOT4 CCR4-NOT transcription complex, subunit 4 4850 ENSG00000080802
2  ENSG00000109111 NA SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 6830 ENSG00000109111
3  ENSG00000160445 NA ZER1 zer-1 homolog (C. elegans) 10444 ENSG00000160445


Database:Transcription Target       Name:hsa_CAGNYGKNAAA_UNKNOWN       ID:DB_ID:2005
C=74; O=3; E=0.09; R=34.97; rawP=8.97e-05; adjP=0.0015
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000116604 NA MEF2D myocyte enhancer factor 2D 4209 ENSG00000116604
2  ENSG00000105221 NA AKT2 v-akt murine thymoma viral oncogene homolog 2 208 ENSG00000105221
3  ENSG00000142784 NA WDTC1 WD and tetratricopeptide repeats 1 23038 ENSG00000142784




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).